8th International Fresenius Conference "Endocrine Disruptors"

29.11. - 30.11.2017, Park Inn by Radisson Köln City West, Cologne/Germany

8th International Fresenius Conference "Endocrine Disruptors"

Übersicht Programm Referenten Veranstaltungsort Preise & Leistungen

Übersicht

Highlights

Regulatory Developments and socio-political context

  • Update from the European Commission’s DG SANTE: Criteria for ED identification under EU Regulations on plant protection products and on biocidal products
  • Update on the ongoing activities in the ECETOC task force on endocrine disruption
  • ANSES: Past, present and future EDs under REACH – Influence of the criteria on the French strategy
  • A critical view of the common perception of EDs in a societal context

Developments outside of Europe

  • The US Environmental Protection Agency on extrapolation of mammalian-based ToxCast assay results to non-mammalian species to evaluate endocrine disruption

Test Methods

  • EU Commission DG ENV: Activities under the EU strategy for ED – towards better identification of endocrine disruptors
  • OECD guidance document 150 revision

Methods and Epidemiology

  • Update from the EU Joint Research Centre: The EU strategy for ED – towards better identification of endocrine disruptors – addressing the gaps
  • Review of non-monotonic dose responses of substances for human risk Assessment

 

Who do you meet?

Attendee job titles and responsibilities include Directors, Heads, Managers and Consultants of:

  • Toxicology and ecotoxicology
  • Research and development
  • Registration, regulatory affairs
  • Chemical risk assessment
  • Legal and general counselling

Sectors taking part:

  • Chemical/biocide/agrochemical/pharmaceutical/cosmetic industries 
  • Research institutes
  • Regulatory authorities
  • Environmental and health risk consultants
  • Testing laboratories and contract research organisations (CROs)
  • NGOs

Picture credit: @Subbotina Anna/shutterstock.com, @chestra - Fotolia.com

Programm

Get-Together on Tuesday, 28 November 2017
Will you arrive on Tuesday?
Come to the hotel bar at 8 p.m. and meet other participants and experts in a relaxed atmosphere.

Wednesday, 29 November 2017

8.30 Registration and coffee

9.00 Welcome address by Akademie Fresenius and introduction by the Chair

Lennart Weltje, BASF, Germany

Regulatory Developments

9.10 Criteria for ED identification under EU Regulations on plant protection products and on biocidal products: an update

Laura Fabrizi, European Commission, DG SANTE, Belgium

9.40 Past, present and future EDs under REACH: Influence of the criteria on the French strategy

Cécile Michel, French Agency for Food, Environmental and Occupational Health and Safety (ANSES), France

10.10 Panel discussion
10.40 Coffee break

11.10 Industry perspective: Update on the ongoing activities in the ECETOC task force on endocrine disruption

  • ECETOC view on draft EFSA/ECHA guidance on identification of endocrine disruptors
  • Overview of proposed ECETOC approach for identifi-cation of endocrine disruptors
  • ECETOC view on recent thyroid-related activities in the EU

Alex Charlton, Syngenta/ECETOC ED Task Force, United Kingdom

11.40 EU action on endocrine disruptors: some progress, many concerns

  • Why EU action on EDCs is needed
  • The EU’s progress so far – EDC regulation through REACH, and the process of setting criteria to identify EDCs
  • Future prospects for effective identification and control of EDCs in Europe

Michael Warhurst, Chem Trust, United Kingdom

12.10 Ongoing activities within the ECHA ED Expert Group

  • Mandate of the ECHA ED EG
  • Working procedures
  • Special issues

Jürgen Arning, Federal Environment Agency (UBA), Germany

12.40 Panel discussion
13.10 Lunch

Developments Outside Europe

14.40 Extrapolation of mammalian-based ToxCast assay results to non-mammalian species to evaluate endocrine disruption

  • Use of US EPA ToxCast data for screening potential endocrine disrupting chemicals
  • Challenge of extrapolating mammalian-based data to non-mammalian species
  • Evaluation of the ToxCast Assay molecular targets
  • Identification of species similarities and differences based on such data
  • Identification of remaining requirements

Carlie A. LaLone, Environmental Protection Agency, USA

15.10 Brazilian perspective: Current activities concerning Human Health and Endocrine Disruptors

Camila Queiroz Moreira, National Health Surveillance Agency (ANVISA), Brazil

Test Methods

15.40 Activities under the EU strategy for EDs: towards better identification of endocrine disruptors – focus for the future

  • Gaps in test methods
  • Approach to address gaps
  • Factors for prioritising further TG development

Peter Korytar, European Commission DG ENV, Belgium

16.10 OECD guidance document 150 revision

  • Expansion of standardised assays for EDs
  • Use of cross-species data
  • Experiences after 5 years of using GD 150

Jenny Odum, Regulatory Science Associates Ltd. (RSC), United Kingdom

16.40 Evaluating chemicals for endocrine disruption at OECD

  • A discussion of new methods for endocrine screening and testing
  • Validation and harmonisation of alternative methods for evaluating endocrine active chemicals at OECD

Patience Browne, Organisation for Economic Co-operation and Development (OECD), France

17.10 Panel discussion

17.50 End of first day

19.00 Departure time for the evening event
At the end of the first conference day, Akademie Fresenius invites you to a leisurely evening in Cologne. After a short visit to the local Christmas market, we will have dinner at a traditional brewpub with local beer. Don‘t miss out on this opportunity!

Thursday, 30 November 2017

9.00 Welcome address by the Chair

Henrik Holbech, Syddansk Universitet Odense/ECHA ED Expert Group, Denmark

Methods and Endpoints for Measuring Endocrine Activity

9.10 Activities under the EU strategy for EDs: towards better identification of endocrine disruptors – addressing the gaps

  • Recommendations from recent EC funded workshops regarding
  • Thyroid disruption
  • Retinoid signalling pathway
  • Temporal aspects
  • Other aspects

Sharon Munn, European Commission Joint Research Centre, Italy

9.40 Alternative methods as internationally agreed protocols for detecting endocrine disruptors in Europe

  • Alternatives for replacing laboratory animals
  • Biological equivalence concentrations and physiological thresholds
  • Endocrine potential differs from adverse effect

Gregory Lemkine, Laboratoire WatchFrog, France

10.10 Kinetic determination of vitellogenin induction in the epidermis of cyprinid and perciform fishes: Evaluation of sensitive enzyme-linked immunosorbent assays (ELISA)

  • Proof of concept for VTG identification and quantification
  • Advantages of kinetic VTG measurements in terms of animal protection in field monitoring studies, comprehensive data sets for chemical registration procedures and laboratory handling of VTG samples

Bernhard Allner, Gobio-Institute for Ecology of Waters & Applied Biology, Germany

10.40 Panel discussion
11.10 Coffee break

11.40 Differentiating endocrine and non-endocrine toxicities

  • Hazard based regulation means it is important to distinguish endocrine mechanisms from other toxicities
  • Overview of how endpoints may be affected by endocrine and non-endocrine toxicities
  • Recommendations on how to better incorporate these considerations in testing and assessment

James Wheeler, Dow AgroSciences, United Kingdom

12.10 Review of non-monotonic dose responses of substances for human risk assessment

Christophe Rousselle, French Agency for Food, Environmental and Occupational Health and Safety (ANSES), France

12.40 A critical view of the common perception and ongoing debate about EDs

David Zaruk, Odisee University College, Belgium

13.10 Final Remarks and discussion

13.40 Lunch and end of the conference

Referenten

Name

Unternehmen

Allner

Bernard Allner

Gobio Institute for the Ecology of Waters and Applied Biology, Germany

Bernhard Allner has been the Technical Director of the Institute for the Ecology of Waters and Applied Biology since 2002. He is responsible for biological test method based monitoring in the field of municipal and industrial water management. He is member of the ISO standardisation panels for ED and genotoxicity testing methods.

mehrweniger
Arning

Jürgen Arning

Federal Environment Agency (UBA), Germany

Jürgen Arning holds a PhD in Biochemistry and works as a Regulatory Scientist at the German Federal Environment Agency. His main tasks comprise the identification and evaluation of endocrine disruptors in the environment under the REACH framework. Additionally, he is involved in initiating risk management measures for environmental ED and in accompanying scientific research projects. Since 2015 he has been a member of the ECHA Endocrine Disruptors Expert Group.

mehrweniger
Browne

Patience Browne

OECD - Organisation for Economic Co-operation and Development, France

Patience Browne is currently an Administrator in the OECD’s Test Guidelines Programme. Previously she was a Senior Scientist in the US EPA’s Endocrine Disruptor Screening Programme. Patience began her career as a field biologist studying marine mammals in Alaska and has worked in both human health and wildlife science.

mehrweniger

Alex Charlton

Syngenta/ ECETOC ED Task Force, United Kingdom

Fabrizi

Laura Fabrizi

European Commission (DG SANTE), Belgium

Laura Fabrizi works as a Policy Officer at the European Commission, DG for Health and Food Safety (DG SANTE), Unit Pesticides and Biocides. She has been working for 15 years as a researcher in toxicology and food chemistry. Laura has been involved in the work for developing criteria to identify endocrine disruptors in DG SANCO/DG SANTE since 2010.

mehrweniger
Holbech

Henrik Holbech

Syddansk Universitet Odense/ ECHA ED Expert Group, Denmark

Henrik Holbech holds a PhD in Ecotoxicology and currently works as Associate Professor at Department of Biology, University of Southern Denmark. He has been involved in the development of OECD Test Guidelines for Endocrine Disrupters in aquatic vertebrates and invertebrates for more than 15 years. Henrik was selected by the Danish EPA to represent Denmark in the OECD VMG-Eco and ECHA ED expert group.

mehrweniger
Korytar

Peter Korytar

European Commission (DG ENV), Belgium

Peter Korytar holds a PhD in Analytical Chemistry from the Free University of Amsterdam. Before joining the European Commission in 2008, he worked at Wageningen IMARES as a Researcher. At DG Environment, Unit Sustainable Chemicals, he is a Leader of the team in charge of policy development areas such as EDs, chemical mixtures, non-toxic environment strategy and pharmaceuticals in the environment.

mehrweniger
LaLone

Carlie Ann LaLone

Environmental Protection Agency (U.S. EPA), USA

Carlie A. LaLone is a Bioinformaticist at the Mid-Continental Ecology Division, in the Office of Research and Development with the U.S. Environmental Protection Agency. From 2010-2015 she was a postdoctoral Biologist for the US EPA and the University of Minnesota. She serves as a task lead for research aimed at defining the taxonomic relevance of adverse outcome pathway (AOP) knowledge to support regulatory toxicology.

mehrweniger
Lemkine

Gregory Lemkine

Watchfrog, France

Gregory Lemkine is the Founder and Chief Executive officer of Laboratoire WatchFrog. He has a thorough understanding of the technical, scientific side and the marketing of biotechnologies and completed a training/action cycle of HEC school of management. He also holds a PhD in Physiology with a specific interest on the role of hormones to determine neural stem cells.

mehrweniger
Michel

Cécile Michel

French Agency for Food, Environmental and Occupational Health and Safety (ANSES), France

Cécile Michel is a Regulatory Toxicologist at ANSES. After working for the pharmaceutical industry, Cécile has been working at ANSES for 9 years. She is a member of the ED expert group of ECHA.

mehrweniger
Munn

Sharon Munn

European Commission - Joint Research Centre, Italy

Sharon Munn is a Project Manager at the European Commission, in the DG Joint Research Centre. Her background is in human toxicology and risk assessment. She is working in support of the Community Strategy for Endocrine Disruptors focusing on improved approaches for the detection of endocrine disrupting substances.

mehrweniger
Odum

Jenny Odum

Regulatory Science Associates Ltd. (RSC), United Kingdom

Jenny Odum is an Independent Consultant Toxicologist with a broad range of experience. She is an expert in the ED field and a member of OECD groups on testing for endocrine disruption and the development of test guidelines.

mehrweniger

Camila Queiroz Moreira

National Health Surveillance Agency (ANVISA), Brazil

Rousselle

Christophe Rousselle

French Agency for Food, Environmental and Occupational Health and Safety (ANSES), France

Christophe Rousselle is a Toxicologist and currently the Manager of the Chemical Risk Assessment Unit at the French Agency for Food, Occupational and Environmental Health.

mehrweniger
Warhurst

Michael Warhurst

CHEM Trust, United Kingdom

Michael Warhurst has been the Executive Director of CHEM Trust since 2014. At CHEM Trust, a UK registered charity, he works at EU, UK and international levels to prevent man-made chemicals from causing long term damage to wildlife or humans, by ensuring that chemicals which cause such harm are substituted with safer alternatives.

mehrweniger
Weltje

Lennart Weltje

BASF, Germany

Lennart Weltje holds a PhD in Ecotoxicology and Environmental Chemistry and currently works as a Senior Ecotoxicologist at BASF conducting risk assessments for PPPs and biocides. His former stations include the Dutch National Institute for Public Health and the Environment (RIVM).

mehrweniger
Wheeler

James Wheeler

Dow AgroSciences, United Kingdom

James Wheeler works as an Ecotoxicologist for Dow AgroSciences based in the UK. His work focuses on environmental risk assessment and ecotoxicology testing with a particular interest in fish endocrine test methods.

mehrweniger
Zaruk

David Zaruk

Odisee University College, Belgium

David Zaruk is an Environmental-health Risk Governance Analyst and a Professor at Odisee University College and Université Saint-Louis in Brussels. He sits on various research ethics panels and frequently serves as a chair, expert, rapporteur, ethics adviser or evaluator for European-funded research projects. David worked 12 years in chemicals issue management for Solvay, Cefic and Burson-Marstelle.

mehrweniger

Veranstaltungsort

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Innere Kanalstraße 15
50823 Köln
Telefon: +49 221 5701-0
E-Mail: koelnproventhotels.com
www.parkinn-hotel-koeln.de

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