Endocrine Disruptors

This conference delves into the ongoing debate surrounding the complex identification of endocrine disruptors and the implementation of EU regulatory requirements across chemicals legislation. Participants gain practical insights into the application of guidance documents, current testing methods, and the latest scientific and regulatory developments.

12.11. — 13.11.2026
Live Stream
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ÜbersichtProgrammReferent:innenVeranstaltungsortPreise & Leistungen

Übersicht

The identification of endocrine disruptors (EDs) is one of the most complex and fast‑evolving challenges in EU chemicals regulation. Originally driven by the Biocidal Products Regulation (EU) No 528/2012 and the Plant Protection Products Regulation (EC) No 1107/2009, endocrine disruptor assessment has gained further momentum with the introduction of new ED hazard classes under the CLP Regulation. These changes have far‑reaching implications for chemicals regulated under REACH and increasingly affect downstream sectors such as cosmetics, packaging materials, and consumer products.

Featuring high‑level presentations from experts representing authorities, industry, research organisations, and academia, this conference brings together all relevant stakeholders to share the latest regulatory developments, scientific advances and practical implementation challenges related to endocrine disruptors.

Join the discussion, exchange expertise, and ensure your organisation stays ahead of evolving EU endocrine disruptor requirements

The Conference will be taking place in Cologne/Germany on 12 and 13 November 2026 and you can follow all the exciting contributions via our live stream!

Would you instead prefer to join on-site in Cologne? Then you can find further information here.

What our participants think about this event:

“The meeting was truly excellent in every aspect. The lineup of speakers was outstanding. Chairs did a great job. The topics were relevant and triggered very interesting discussions. The meeting was extremely well organized and created an excellent environment that encouraged great interaction and collaboration among participants.“ – Arianna Bassan, Innovatune, Italy

“The Akademie Fresenius Conference on Endocrine Disruptors is the place to be to understand and discuss the challenges associated with the identification and regulation of endocrine disruptors for human health and the environment. Wisely selected speakers are invited to share latest scientific and regulatory developments, triggering lots of exchanges and discussions with a captivated and engaged audience. A great event “where experts meet”, perfectly orchestrated by a dedicated and very professional organizing team.“ – Laurant Lagadic, Bayer AG, Germany

“An annual meeting of experts on endocrine disruption, bringing together authorities, industry, laboratories and consultants focused on human health and environment, with a single goal: where are we on this topic? Critical issues? Perspectives? Very informative and rich in encounters and knowledge! Thanks to Akademie Fresenius!“ – Maurine Duplaa, CEHTRA, France

“A good place where regulatory science can meet industry needs and case studies.“ – Jürgen Arning, Umweltbundesamt Dessau-Roßlau (UBA), Germany

Who should attend this conference?

Professionals working in the fields of:

  • Toxicology and ecotoxicology
  • Risk assessment
  • Research and development
  • Registration and regulatory affairs
  • Legal and general counselling

Sectors that should take part:

  • Chemical, biocide and agrochemical industries
  • Pharmaceutical and cosmetic industries
  • Packaging and consumer‑product manufacturers
  • Research institutes
  • Regulatory authorities
  • Environmental and health risk consultants
  • Testing laboratories and contract research organisations (CROs)
  • NGOs

Picture Credit: © Subbotina Anna/shutterstock.com, © chestra - Fotolia.com

 

Programm

Programme Preview

We are delighted to share a preliminary preview of the programme. The following contributions have already been confirmed:

Legislative Frameworks, Regulatory Developments and Implementation
Regulation of Chemicals Demands Assessment of Risks Rather than Identification of Hazards Only

Philip Marx-Stölting, German Federal Institute for Risk Assessment (BfR), Germany

Deriving Endocrine Disruptor Predicted No Effect Concentrations for the Environment

Becky Brown, wca, United Kingdom

ED Assessments in the Pesticides Area: Experience from Greece

Dimitra Nikolopoulou, Benaki Phytopathological Institute, Greece

Current Status of Implementing Endocrine Disruptor Requirements across Regulations and Challenges Related to CLP

Christine Walter, Regulatory Science Associates (rsa), United Kingdom

Practical Challenges: Managing ED Requirements Along Complex Supply Chains
  • ED in the complex food contact material supply chain
  • ED substances of “interest” – safety considerations: chemical versus biological assessment
  • Analytical challenges for the determination of EDs
  • Risk assessment responsibilities in the complex value chain

Thomas Gude, Independent Consultant, Germany

Developments in Testing Methods and New Approach Methodologies (NAMs)
Roadmap for Phasing Out Animal Testing

Katrin Schütte, European Commission, Belgium (virtually)

From Lab to Life: Qualification as a Bridge to Fast-Track the Use of Animal-Free Methods in Risk Assessment
  • Addressing the regulatory gap: The challenges of integrating non-standard approaches into risk assessment
  • A proposed qualification system for improving regulatory acceptance of NAMs
  • Nanomaterial risk assessment as a pilot application and proof of concept
  • Stakeholder engagement and implementation pathway

Andrea Haase, German Federal Institute for Risk Assessment (BfR), Germany

The Use of NAMs to Build the Weight of Evidence: Regulatory Case Studies

Gregory Lemkine, Laboratoire Watchfrog, France

PBK Modelling of Thyroid Effects: From Rats to Humans
  • Development of a PBK-QST model integrating species-specific regulation of TSH, thyroid hormone (T3/T4) synthesis, transport and clearance
  • Model predictions based on kinetic data and comparative liver enzyme induction across species
  • Interpretation of potential impacts on human thyroid hormone levels and implications for thyroid-mediated neurodevelopmental toxicity

Stephanie Melching-Kollmuss, BASF Agricultural Solutions Deutschland, Germany

Assessing Population Relevance of Endocrine Disrupting Effects in Fish and Amphibians: An Update from the SETAC MAPPED Workshops
  • Consideration of EAS-modalities in fish and T-modality in amphibians
  • Use of the pathway to harm concept and selection of focal species
  • Review and recommendations for models: processes included, scenarios modelled, threshold for relevance
  • Presentation of a modelling example

Charles Hazlerigg, Enviresearch, United Kingdom

Referent:innen

Folgende Referierende haben bereits zugesagt, weitere folgen in Kürze:

Name

Unternehmen

Brown

Becky Brown

wca, United Kingdom

Becky Brown is a Director at WCA, an independent employee-owned environmental consultancy. She is an ecotoxicologist specialising in endocrine disruptor assessments and the interpretation of the environmental effects of active substances. Recent projects include highlighting some of the issues associated with measuring vitellogenin in fish, supporting the European Chemicals Agency through a series of internal and external workshops on the new ED hazard criteria, and supporting the Environment Agency of England in developing approaches to derive threshold levels for endocrine-disrupting substances.

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Gude

Thomas Gude

Independent Consultant, Switzerland

Thomas Gude is Managing Director of Thomas Gude GmbH, which specialises in consulting in the areas of food contact materials, food and non-food. After about 30 years with authorities, the pharmaceutical and chemical industries and a long time as the operational manager of a Swiss laboratory, he now deals with risk assessments, especially in the food contact and consumer goods sector. In addition, he teaches at various universities and technical colleges, in particular at ETH Zurich.

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Haase

Andrea Haase

German Federal Institute for Risk Assessment (BfR), Germany

With a background in biochemistry, toxicology, and pharmacology, Dr. Andrea Haase completed her PhD at the University of Heidelberg and later obtained her habilitation at Freie Universität Berlin. She is Head of the Fibre and Nanotoxicology Unit and Deputy Head of the Department of Chemical and Product Safety at the German Federal Institute for Risk Assessment (BfR). Her research focuses on New Approach Methodologies (NAMs), nanotoxicology, and next generation risk assessment for nano- and other advanced materials. She is a member of the EFSA Nano Network, and chairs the German Interagency Working Group on Advanced Materials.

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Hazlerigg

Charles Hazlerigg

Enviresearch, United Kingdom

Charles Hazlerigg is an Ecotoxicologist, UKRI Future Leaders Fellow and IBERA Diplomate based at Enviresearch, UK. He uses ecological modelling approaches to better understand the impacts of chemical stressors on populations. As a member of the Expert Committee on Pesticides (ECP) he also contributes independent, impartial advice to the UK government on the science relating to pesticides.

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Adam Jonáš

REGARTIS, Czech Republic

Lemkine

Gregory Lemkine

Laboratoire Watchfrog, France

Marx-Stölting

Philip Marx-Stölting

German Federal Institute for Risk Assessment (BfR), Germany

Philip Marx-Stoelting, Dr. rer. nat., ERT, is serving at the German Federal Institute for Risk Assessment as a scientific director heading the unit ‘Testing and assessment strategies’ in the pesticides safety department and the BfR working groups on endocrine disruptors and assessment concepts. He is involved in several large research projects on NAM development and NGRA including RiskHunt3R, Envesome or PARC, where he is leading the work-package ‘hazard assessment’. He has overseen more than 1000 risk assessments and has published more than 90 research papers and standard text book chapters. Philip is a member of the editorial board of Toxicology Letters and Reg Tox Pharm. He is also involved in several expert panels on EU and international (OECD) level and chairing the 3R working group of the German Society for Toxicology (GT) and the Mixture working group of ILMERAC.

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Samuel Maynard

AstraZeneca, United Kingdom

McVey

Emily McVey

National Institute for Public Health and the Environment (RIVM), The Netherlands

Emily McVey is an experienced Regulatory Toxicologist and works at the Dutch National Institute for Public Health and the Environment (RIVM). Her specialties include environmental toxicology, wild vertebrates (birds, mammals, amphibians, fish), molecular mechanisms of toxicity, neurodevelopmental toxicity and endocrine disruption testing and assessment.

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Melching-Kollmuss

Stephanie Melching-Kollmuss

BASF Agricultural Solutions Deutschland, Germany

Stephanie Melching-Kollmuss has been working in the field of regulatory toxicology for chemicals and plant protection products for over 20 years, for more than 15 years at BASF SE. Her special interest is in endocrine disruption, mainly on the thyroid modality. Stephanie chaired the ECETOC Thyroid Task Force on how to assess thyroid-hormone related neurodevelopmental toxicity, which resulted in a number of publications; based on which criteria to support EU classifications were developed and applied to data-rich case studies.

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Nikolopoulou

Dimitra Nikolopoulou

Benaki Phytopathological Institute, Greece

Dimitra Nikolopoulou is a European Registered Toxicologist (ERT) and has worked as a Regulatory Toxicologist at the Benaki Phytopathological Institute (BPI), the Greek Competent Authority for the risk assessment of pesticides and biocides, since 2000. She routinely conducts and supervises the evaluation of in silico, in vitro and in vivo toxicological and endocrine-disruption data relevant to human health, in accordance with EFSA, ECHA, OECD and USEPA guidance. She has contributed to the preparation of more than 30 Draft Assessment Reports, Renewal Assessment Reports and Competent Authority Reports. She serves as the Greek national representative at EFSA Pesticide Peer Review meetings on mammalian toxicology and as a Core Member of the ECHA Biocidal Products Committee Working Group on Human Health. She has also contributed to EFSA Working Groups on the cumulative risk assessment of pesticides, metabolites common to several pyrazole active substances, and cyclamates. She has participated in several EU-funded projects and partnerships, including PARC, EuroMix and EFSA projects providing technical support in toxicology. Within PARC, she leads Task 6.3 on the review of risk assessment methodologies and manages the project “Towards a Harmonised Approach in Chemical Risk Assessment”. She is also involved in implementing case studies on endocrine-disruption assessment, integrated approaches to testing and assessment (IATA) for genotoxicity and human relevance.

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Schütte

Katrin Schütte

European Commission, Belgium

Katrin Schütte is a policy officer at the EU Commission's Directorate for the Environment, which she joined in 2014. Her responsibilities cover several aspects of REACH as well as the area of non-animal testing methods and in this context the drafting and implementation of the EU Roadmap towards phasing out animal testing for chemical safety assessments.

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Walter

Christine Walter

Regulatory Science Associates (rsa), United Kingdom

Christine Walter is a regulatory toxicologist and has been working as a consultant for Regulatory Science Associates (RSA) since 2023. Previously, she gained more than 15 years of experience in toxicology and regulatory roles in both the agrichemical industry and pharmaceutical consultancy sectors. She has contributed to multiple human risk assessments including ED Assessments, investigative mode of action work and regulatory submissions. She holds a PhD in Biochemistry.

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Weltje

Lennart Weltje

BASF Agricultural Solutions Deutschland, Germany

Lennart Weltje holds a PhD in ecotoxicology and environmental chemistry and currently works as a Senior Ecotoxicologist at BASF Agricultural Solutions Deutschland conducting risk assessments for PPPs and biocides. He is also an honorary Professor at the Faculty of Agricultural Sciences of the Georg-August University in Goettingen. His former stations include the Dutch National Institute for Public Health and the Environment (RIVM).

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12.11. — 13.11.2026,  Best Western Plus Hotel Köln City

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